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Wednesday, December 13, 2006

CoLocalizer Pro papers keep coming...

Dr. Osvaldo Rey and colleagues from the University of California at Los Angeles published a very interesting paper about the role of calcium-sensing receptor (CaR) in the generation of transient Ca2+ oscillations. Dr. Rey used CoLocalizer Pro software to elegantly quantify the colocalization of CaR and transient receptor potential gene, TRPC1, according to Manders' overlap coefficient. They employed CoLocalizer Pro to quantify colocalization of CaR and TRPC1 and presented corresponding scatter grams. The paper is a good read and leaves a very positive impression. The paper appeared in the Journal of Biological Chemistry (281:38730-38737 (2006), one of the best journals in the medico-biological field.

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